Livestock Studies 2015, Vol 55, Num, 2     (Pages: 045-049)

The effect of environmental factors and Growth Hormone Receptor gene polymorphism on growth curve and live weight parameters in buffalo calves

Koray ÇELİKELOĞLU 1 ,Metin ERDOĞAN 2 ,Serdar KOÇAK 1 ,Fahriye ZEMHERİ 2 ,Mustafa TEKERLİ 1

1 Department of Zootechny, Faculty of Veterinary Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey
2 Dept. of Veterinary Biology and Genetics, Faculty of Veterinary Medicine, Afyon Kocatepe University, Turkey
- This study was conducted to determine the effects of some environmental factors and growth hormone receptor gene polymorphisms (GHR) on Brody growth curve coefficients and different body weights parameters in buffalo calves. The records and blood samples of 27 buffalo calves, born in 2009, bred at Afyon Kocatepe University Animal Research Center were analyzed. A, B and k parameters for the Brody model were estimated as 366.589±31.698, 0.932±0.011 and 0.002±0.000 respectively. In addition, live weights at birth, 180 and 360 days were 30.696±1.043 kgs, 121.701±5.071 kgs and 188.834±8.442 kgs respectively. Three polymorphic regions were detected at G3676A, G3679A and G3680del bases in exon 10 of the GHR gene. Effects of sex on parameter A and birth weight on weight at 180 days were statistically significant (P<0.05). Findings indicated that G3676A and G3679A mutations and haplotypes consisting of mentioned SNPs may result in significant differences in growth traits, but the available data were not enough to reveal this fact. Keywords : Water buffalo, growth curve, growth hormone receptor, SNP