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¹ Ankara Üniversitesi Veteriner Fakültesi Farmakoloji ve Toksikoloji Anabilim Dalı, Ankara - Drugs used in veterinary medicine find applications for different purposes. The rational use of these drugs is extremely important. This situation is especially important for animal health, public health and environmental health. With the use of these drugs, beneficial effects can be formed, but some harmful effects also can be occurred. Especially drug residues and antibacterial resistance are extremely important in these harmful effects. In this review, a general evaluation and actual information on the two undesirable effects were presented. Approaches that could be done to prevent these effects, which are also important in terms of public health, were expressed. Keywords : Veterinary, drug, undesirable effect, residue, resistance