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¹ Lalahan Hayvancılık Merkez Araştırma Enstitüsü Müdürlüğü - IFNτ acts on uterine epithelium to suppress transcription of the genes for estrogen receptor and oxytocin receptor. This blocks development of the uterine luteolytic mechanism. Maintenance of progesterone secretion by the corpus luteum ensures establishment and maintenance of pregnancy. Secretion of IFNτ on days 12-15 for sheep and days 14-17 for cows and goats is essential for pregnancy recognition. Keywords : Interferon Tau, Pregnancy